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KMID : 0360919610040120039
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Journal of the Korean Medical Association
1961 Volume.4 No. 12 p.39 ~ p.62
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Physiological Studies On Acute Carbon Monoxide Poisoning in the Anesthetized Dog
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Abstract
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In view of the frequent incidence of acute carbon monoxide (CO) poisoning among air crews as well as among Korean residents who are daily using briquettes, the author, undertook in past a series of studies concerning.
(1) the tolerance of mice to CO and (2) changes in erythrocyte counts and hematocrit ratios in case of CO intoxication. In these investigations the author derived a formula which would enable us to compute the appearance time of the respiratory arrest when breathing various concentrations of CO. Moreover, it was pointed out that there is a considerable iudividnal difference in the appearance time of respiratory arrest for a given CO concentration. Although it has been previously stated by various investigators that an in crease in the hemoglobin concentration during CO exposure is one of the most important factors which increase the tolerance of animals to CO intoxication there was no obvious correlation between the degree of increase in the hemoglobin´ concentration and the appearance time of the respiratory arrest during the acute CO exposure
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KEYWORD
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